Probing the molecular interactions between pharmaceutical polymeric carriers and bile salts in simulated gastrointestinal fluids using NMR spectroscopy
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چکیده
منابع مشابه
Interactions between Bacteria and Bile Salts in the Gastrointestinal and Hepatobiliary Tracts
Bile salts and bacteria have intricate relationships. The composition of the intestinal pool of bile salts is shaped by bacterial metabolism. In turn, bile salts play a role in intestinal homeostasis by controlling the size and the composition of the intestinal microbiota. As a consequence, alteration of the microbiome-bile salt homeostasis can play a role in hepatic and gastrointestinal pathol...
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It has been known that the addition of bile salts to lecithin organosols induces the formation of reverse wormlike micelles and that the worms are similar to long polymer chains that entangle each other to form viscoelastic solutions. In this study, we further investigated the effects of different bile salts and bile acids on the growth of lecithin reverse worms in cyclohexane and n-decane. We ...
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ژورنال
عنوان ژورنال: Journal of Colloid and Interface Science
سال: 2019
ISSN: 0021-9797
DOI: 10.1016/j.jcis.2019.05.002